Throughout its history the Robert Wood Johnson Foundation (RWJF) has made a deep commitment to nursing, investing more than $592 million in programs to sustain, grow, and reshape the nurse workforce. In recent years the foundation has adopted strategies to expand the impact and reach of its nursing grants. The RWJF supported the 2010 Institute of Medicine (IOM) study on the future of nursing, which envisioned expanded roles for nurses in the US health care system. Since then, the RWJF has invested heavily in implementing the IOM report’s recommendations through the Future of Nursing: Campaign for Action, a partnership with AARP. In the past three years, that report has been the most-read IOM publication. Also, “action coalitions” are working in fifty states and the District of Columbia to implement its recommendations; philanthropic partners are also supporting implementation; and leaders in academic and clinical nursing settings continue their work to advance nurse education, changes in scope of practice, and other IOM recommendations.